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Can a woman use bone marrow to get pregnant

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Credit: Getty Images. The study shows that when an egg is fertilized, stem cells leave the bone marrow and travel via the bloodstream to the uterus, where they help transform the uterine lining for implantation. If the lining fails to go through this essential transformation, the embryo cannot implant, and the body terminates the pregnancy. But knowing that bone marrow has a significant role is a paradigm shift.

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Cells that make bone marrow also travel to the womb to help pregnancy

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Since the late s, scientists have explored how to produce sperm where all of the chromosomes come from a female donor. Creating female sperm was first raised as a possibility in a patent filed in [3] by injecting a woman's cells into a man's testicles, though the patent focused mostly on injecting altered male cells into a man's testes to correct genetic diseases.

In , Japanese scientists partially confirmed such techniques by creating chicken female sperm in a similar manner. It is therefore concluded that most of the W-bearing PGC could not differentiate into spermatozoa because of restricted spermatogenesis. One potential roadblock to injecting a woman's cells into a man's testicles is that the man's immune system might attack and destroy the woman's cells. In usual circumstances, when foreign cells such as cells or organs from other people, or infectious bacteria are put into a human body, its immune system will reject such cells or organs.

However, a special property of a man's testicles is that they are immune-privileged , that is, a man's immune system will not attack foreign cells such as a woman's cells injected into the sperm-producing part of the testicles. Thus, a woman's cells will remain in the man's testicles long enough to be converted into sperm. However, there are more serious challenges. Biologists have well established that male sperm production relies on certain genes on the Y chromosome , which, when missing or defective, lead to such men producing little to no sperm in their testicles.

An analogy, then, is that a cell from a woman has complete Y chromosome deficiency. While many genes on the Y chromosome have backups homologues on other chromosomes, a few genes such as RBMY on the Y chromosome do not have such backups, and their effects must be compensated for to convert cells from a woman into sperm.

In , a patent application was filed [4] on methods for creating human female sperm using artificial or natural Y chromosomes and testicular transplantation. In Chinese research scientists produced 29 viable mice offspring from two female mother mice by creating sperm-like structures from haploid embryonic stem cells using gene editing to alter imprinted regions of DNA.

Experts noted that there was little chance of these techniques being applied to humans in the near future. Scientists from the University of Newcastle upon Tyne led by biologist Karim Nayernia discovered a method of creating partly developed sperm cells, otherwise known as "spermatogonial" stem cells, from the bone marrow of male volunteers, entirely in-vitro outside the human body , and is seeking funding to see whether such techniques can be used to make female sperm.

If created, a "female sperm" cell could fertilize an egg cell, a procedure that, among other potential applications, might enable female same-sex couples to produce a child who would be the biological offspring of their two mothers. It is also claimed that production of female sperm may stimulate a woman to be both the mother and father similar to asexual reproduction of an offspring produced by her own sperm. Many queries, both ethical and moral, arise over these arguments.

From Wikipedia, the free encyclopedia. Female sperm can refer to either: A sperm which contains an X chromosome , produced in the usual way by a male, referring to the occurrence of such a sperm fertilizing an egg and giving birth to a female.

A hypothetical sperm which artificially contains genetic material from a female. This article focuses on the second definition.

Human Samesex Reproduction Project. Development, Growth and Differentiation. Patent Office. Retrieved Gregory Aharonian. The Times. Cell Stem Cell. London: The Guardian. Newcastle University. Archived from the original on London: Daily Telegraph. London: The Independent. New Scientist. Categories : Sexuality. Hidden categories: All articles with dead external links Articles with dead external links from November Namespaces Article Talk.

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Bone marrow-derived cells play a role in changes to the mouse uterus before and during pregnancy, enabling implantation of the embryo and reducing pregnancy loss, according to research published September 12 in the open-access journal PLOS Biology. Although the study was done in mice, it raises the possibility that dysfunction of bone marrow-derived progenitor cells may contribute to implantation failure and pregnancy loss in women. Bone marrow progenitors can become either blood or tissue cells. Within the uterus they differentiate into endometrial tissue cells in the lining of the womb, but until now it was not known if they have a function in pregnancy. Reshef Tal and colleagues from Yale School of Medicine developed a bone marrow transplantation protocol that preserved ovary and reproductive function, allowing them for the first time to track these cells in pregnancy, showing that during pregnancy cells from the bone marrow were preferentially recruited to the uterus and were concentrated near the site of implantation, on the maternal side of the placenta.

Follow Slashdot blog updates by subscribing to our blog RSS feed. I guess after being told to "Go Fuck Yourself" for so many years, these scientists finally found a way to do it. There will be some interesting debates raging about this one for a long time.

Stem cells have generated such an enormous amount of interest, in part, because of their applications related to areas such as fertility and genetics. In that same light, their interest for solving reproductive challenges has also generated a great deal of controversy. This is particularly true in the application of stem cells to facilitate reproduction for gay couples. At present, there are a number of research laboratories that are focused on the creation of cells that are genetically male but have been produced from eggs.

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Your email address is used to log in and will not be shared or sold. Read our privacy policy. If you are a Zinio, Nook, Kindle, Apple, or Google Play subscriber, you can enter your website access code to gain subscriber access. Your website access code is located in the upper right corner of the Table of Contents page of your digital edition. Sign up for our email newsletter for the latest science news. The experiment marks the first time that any nonreproductive human tissue has been transformed into gametes. If the cells can be grown into mature sperm, the technique would allow men without functioning sperm, or even testes, to father children. Their offspring would always be daughters, though, because sperm made from a female cell would always carry an X instead of a Y chromosome.

Stem Cells and Same Sex Reproduction

The study shows that when an egg is fertilized, stem cells leave the bone marrow and travel via the bloodstream to the uterus, where they help transform the uterine lining for implantation. If the lining fails to go through this essential transformation, the embryo cannot implant, and the body terminates the pregnancy. But knowing that bone marrow has a significant role is a paradigm shift. In this study, the researchers were able to prove the physiological relevance of stem cells to pregnancy.

Since the late s, scientists have explored how to produce sperm where all of the chromosomes come from a female donor. Creating female sperm was first raised as a possibility in a patent filed in [3] by injecting a woman's cells into a man's testicles, though the patent focused mostly on injecting altered male cells into a man's testes to correct genetic diseases.

But recently a team of scientists announced they had made artificial sperm from human bone marrow , and media reports abounded with the dire news that my goodfellas and by extension, me had been rendered unnecessary. There are at least half a dozen reasons why such speculation is silly, some scientific and some practical. For example, as long as sex feels good and remains no more expensive than dinner and a bottle of wine, most people will use natural-grown sperm.

Will science render men unnecessary?

By Roxanne Khamsi. In a first step towards creating artificial sperm cells, researchers have turned human bone marrow tissue into primitive sperm cells. If these precursor cells can be coaxed into becoming fully functioning sperm cells, the technique could allow infertile men to father their own children, and even allow women to produce their own sperm. But experts caution that provoking the sperm precursors to fully mature presents a serious challenge.

 Стратмора надо остановить! - кричал Хейл.  - Клянусь, я сделаю. Этим я и занимался сегодня весь день - считывал тексты с его терминала, чтобы быть наготове, когда он сделает первый шаг, чтобы вмонтировать этот чертов черный ход. Вот почему я скачал на свой компьютер его электронную почту. Как доказательство, что он отслеживал все связанное с Цифровой крепостью.

Bone marrow may be the missing piece of the fertility puzzle

В глубине души она понимала, что абсурдно обвинять в нерадивости Стратмора, который был беззаветно предан своему делу и воспринимал все зло мира как свое личное. Попрыгунчик был любимым детищем коммандера, смелой попыткой изменить мир. Увы, как и большинство других поисков божества, она закончилась распятием. - Хорошо, - сказала.  - Я немного погорячилась. - Немного? - Глаза Бринкерхоффа сузились.  - У Стратмора стол ломится от заказов. Вряд ли он позволил бы ТРАНСТЕКСТУ простаивать целый уик-энд.

Jun 27, - If a woman chose to do so, speculated tabloid journalists, she could make sperm from her own bone marrow, fertilize another woman's egg — and voila! dinner and a bottle of wine, most people will use natural-grown sperm.

 El anillo. Внезапно Беккера охватило чувство, которого он никогда прежде не испытывал. Словно по сигналу, поданному инстинктом выживания, все мышцы его тела моментально напряглись.

Bone marrow stem cells may be vital for pregnancy

Его слова буквально обожгли Сьюзан. - Первичное! - воскликнула. И повернулась к Джаббе.

Bone stem cells turned into primitive sperm cells

КОЛИЧЕСТВО ДЕШИФРОВОК О Мидж постучала пальцем по этой цифре. - Я так и думала. Деление на ноль. Бринкерхофф высоко поднял брови.

Сьюзан бессильно прижалась к двери, за которой, всего в нескольких сантиметрах от нее, работала вентиляция, и упала, задыхаясь и судорожно хватая ртом воздух.

Может быть, можно взглянуть? - Он встал и начал обходить круг терминалов, двигаясь по направлению к. Сьюзан понимала, что сегодня любопытство Хейла может привести к большим неприятностям, поэтому быстро приняла решение. - Это диагностика, - сказала она, взяв на вооружение версию коммандера. Хейл остановился: - Диагностика? - В голосе его слышалось недоверие.

Female sperm

 Но вы же не знали. Стратмор стукнул кулаком по столу. - Я должен был знать. Да взять хотя бы его электронное имя.  - Боже мой, Северная Дакота. Сокращенно NDAKOTA. Подумать .

 Ein Vorschlag? - У немца перехватило дыхание.  - Предложение. - Да. Я могу прямо сейчас отвести вас в участок… - Беккер выразительно замолчал и прищелкнул пальцами.

Comments: 3
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  3. Kerisar

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